Developing Biomarkers for Better Patient Care

The Program of Applied Translational Research (PATR) is dedicated to the process of applying discoveries generated in the laboratory and in preclinical experiments, to the development of clinical studies, and to the design of clinical trials. As a critical component of this mission, the Program also seeks to conduct translational research to advance the understanding of novel biomarkers so as to enhance their clinical utility in complex diseases.

The Program develops novel translational research methodologies for assessing biomarker performance and identifies innovative strategies to treat complex clinical disorders, such as kidney injury associated with surgery and post-transplantation kidney injury. A large biosample repository with associated bioinformatics has been established to support all phases of translational research and biomarker development. The Program also recruits and trains students and young scientists in translational research education. 

The Program is led by Dr. Chirag Parikh MD, PhD, Associate Professor of Medicine (Nephrology) and stems from his principal research interest on the translation and validation of novel biomarkers for the diagnosis and prognosis of acute kidney injury.